Manchester United manager Sir Alex Ferguson expects Jonny Evans to be out for two weeks with a calf injury, adding to club's defensive problems.
Evans was forced off at half-time in the 5-0 victory over Wigan, leaving United without a fit centre-back.
"We have had a nightmare the last few days," said Ferguson. "Phil Jones and Chris Smalling have both been ill.
Man Utd's current injury list
Nemanja Vidic (knee)
Darren Fletcher (illness)
Rio Ferdinand (back)
Michael Owen (thigh)
Anderson (knee)
Tom Cleverley (ankle)
Fabio (hamstring)
Phil Jones (illness)
Ashley Young (knee)
Chris Smalling (illness)
Jonny Evans (calf)